Answer to question; Avast & AVG & MSE
Best practice is to use just one product for one thing,and to not have two antivirus installed.
Best practice is to use also all from same company.(for best compatibility)
But if u know what you are doing then u can mix,but then u will not ask this question,but just follow best practice rule to not install two or more antivirus product.
Advice: Avoid MSE.
Advice 2: Comodo firewall is really good ,but it will ask you questions,what many don't like,but firewall rules are good only and only if you (owner or administrator) make it.
At least that is in Comodo firewall in interactive way, professionals uses and write complex tables,but its same principle of manual entering.(so,answering yes once,yes always,not now,never cant be avoided without losing real protection)
experience and knowledge