My wife got some of that "heart healthy" Bisquick and dislikes it. Read the ingredients label. The original Bisquick contains Soybean/Cottonseed oil. The "heart healthy" contains Canola oil. Soybean oil will have more flavor than Canola. However, the real argument is not the omegas nor anything else but the one thing most commonly done to oils: the normal Bisquick has "Partially hydrogenated Soybean/Cottonseed oil." Oops. The "Heart Healthy" has non-hydrogenated Canola. The Canola isn't the healthy part; the not being hydrogenated is, as that running hydrogen gas thru the oil (invented to lower the solidification temperature, making potato chips possible) has been shown to be very harmful to the heart and circulatory system. Well, duh. If it solidifies at a lower temperture outside the body, it's solidifying at a lower temperature inside the body, too. Sheesh. The rest of your question is that peanut oil and olive oil have better flavors, and I prefer cooking with the latter.